Immunosuppression in Solid Organ Transplantation
Infections After Solid Organ Transplantation
Malignancy After Solid Organ Transplantation
Organ Transplantation in HIV-Infected Individuals
Critical Care Management of the Deceased Donor
Hematopoietic Cell Transplantation (HCT)
Recognize basic immunosuppressive approaches to solid organ transplant recipients.
Anticipate common infectious and malignant complications of solid organ transplantation.
Be aware of indications for solid organ transplantation and critical care issues early and late after major types of transplantation.
Know common challenges to donor management in the ICU.
Identify major causes of critical illness after hematopoietic cell transplantation.
Solid organ transplantation is frequently complicated by critical illness, and care of these patients requires a basic understanding of immunosuppressive therapy and the overwhelming infections and serious malignancies that can occur. An awareness of indications for transplantation in critically ill patients and complications of common transplant procedures improves medical decision making in the ICU. Deterioration in graft function that occurs over time contributes to critical illness in recognizable and unique ways for each kind of transplanted organ. Management of organ donors presents challenges that can be anticipated by the intensive care physician. Patients who receive hematopoietic cell transplantation are at risk to develop numerous early and late complications that require care in the ICU.