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Chapter 26. Genetic and Immunologic Aspects of Sleep Disorders

James M. Parish, MD, FCCP
DOI: 10.1378/smbr.4th.271
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Excerpt

  • Understand genetic basis of circadian rhythm

  • Understand the genetic basis of both normal sleep and of common sleep disorders

  • Understand the association of narcolepsy with human leukocyte antigen phenotypes and with hypocretin deficiency

  • Understand that infection due to viruses and bacteria are associated with changes in inflammatory mediators that have effects on sleep

  • Recognize that insufficient sleep may have adverse effects on immune function

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