Interpreting Clinical Research
Measures of Association
Quantifying Effect Size
P values and Confidence Intervals
Diagnostic Tests: Sensitivity, Specificity, and Beyond
Summarize important elements of clinical research study design and interpretation.
Explain the common measures of association used in clinical research studies.
Describe concepts of statistical testing relevant to research in ICUs.
Explain basic elements of interpreting diagnostic tests in medicine.
In order to apply existing research evidence to patient care, clinicians must be able to critically appraise the literature. Doing so requires understanding of the strengths and weaknesses of various research designs, as well as biases that can occur in the collection and analysis of data. In addition, clinicians should be able to understand and apply basic concepts of diagnostic testing such as sensitivity, specificity, and positive predictive value in order to fully appreciate the meaning of the tests they order for their patients. These topics are reviewed.